Registered: Oct 2010 Posts: 33316 - Threads: 426 Location: london
Quote:
NeonBlue wrote on 21-05-2014 12:50 PM
Yeah I got that you muppet.
the clue is in it's name.
here's another one for you.
Also there is a piece doing the rounds about a hot spoon getting rid of mosquito bites, seemingly not so great if you read this
According to this paper, immunoglobulins (specifically IgG), the stuff that binds to the antigens introduced by a mosquito and cause swelling, start to denature at around 60°C (see page 401), which is probably not a safe temperature to expose your skin to.
As for your second question, it would take between less than one to 25 hours (depending on the temperature) to fully denature the antibodies (see page 399). Of course, it might take a bit longer since there's all that mass between the antibodies and the spoon, and you'll probably get some nice blisters in the process, but it gives a nice idea of how long you're supposed to place a heated spoon on a mosquito bite to reduce swelling. So technically, yes, putting a hot spoon on a mosquito bite could theoretically lessen the reaction.
or this
Antibodies (or immunoglobulins) don't cause the swelling, and you wouldn't want to denature them since they help your body neutralize the foreign agents introduced by a mosquito bite. AFAIK histamine (what causes the itch) is pretty heat-resistant. That's why heat doesn't inhibit histamine-induced itches in patients with dermatitis but it does in healthy subjects. So heat doesn't actually destroy the protein that's causing the itch.
The reason extreme heat works for victims is largely because it shares the same nerve pathway as itches. By overloading the pain-itch receptors with pain-heat, the pain-itch pathway is eventually overloaded and shuts down.
And I don't know if the temperature required to denature alboserpin (the anticoagulant in mosquito saliva that our bodies react to) would be safe for us. Serpins are only sensitive to denaturation at temperatures above 60°C, and that temperature causes sublethal injury to red blood cells if exposed for 1.2 seconds and a 3rd degree burn on your skin if exposed for 5 seconds.
And those who were seen dancing were thought to be insane by those that could not hear the music -Nietzsche
Registered: Sep 2001 Posts: 2659 - Threads: 68 Location: A wretched hive of scum and villainy
Quote:
Quin. wrote on 21-05-2014 12:53 PM
the clue is in it's name.
here's another one for you.
Also there is a piece doing the rounds about a hot spoon getting rid of mosquito bites, seemingly not so great if you read this
According to this paper, immunoglobulins (specifically IgG), the stuff that binds to the antigens introduced by a mosquito and cause swelling, start to denature at around 60°C (see page 401), which is probably not a safe temperature to expose your skin to.
As for your second question, it would take between less than one to 25 hours (depending on the temperature) to fully denature the antibodies (see page 399). Of course, it might take a bit longer since there's all that mass between the antibodies and the spoon, and you'll probably get some nice blisters in the process, but it gives a nice idea of how long you're supposed to place a heated spoon on a mosquito bite to reduce swelling. So technically, yes, putting a hot spoon on a mosquito bite could theoretically lessen the reaction.
or this
Antibodies (or immunoglobulins) don't cause the swelling, and you wouldn't want to denature them since they help your body neutralize the foreign agents introduced by a mosquito bite. AFAIK histamine (what causes the itch) is pretty heat-resistant. That's why heat doesn't inhibit histamine-induced itches in patients with dermatitis but it does in healthy subjects. So heat doesn't actually destroy the protein that's causing the itch.
The reason extreme heat works for victims is largely because it shares the same nerve pathway as itches. By overloading the pain-itch receptors with pain-heat, the pain-itch pathway is eventually overloaded and shuts down.
And I don't know if the temperature required to denature alboserpin (the anticoagulant in mosquito saliva that our bodies react to) would be safe for us. Serpins are only sensitive to denaturation at temperatures above 60°C, and that temperature causes sublethal injury to red blood cells if exposed for 1.2 seconds and a 3rd degree burn on your skin if exposed for 5 seconds.
spoons lol
i don't know about the science, but hold the lit end of a fag a few mill over the bite for 2 to 3 seconds or so will take away the itching
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Registered: Oct 2010 Posts: 33316 - Threads: 426 Location: london
Quote:
Guile wrote on 21-05-2014 01:43 PM
spoons lol
i don't know about the science, but hold the lit end of a fag a few mill over the bite for 2 to 3 seconds or so will take away the itching
The other half thought that it sounded like a good idea, seeing as she works in a school i had to point out that walking around with a spoon and a lighter isn't really a good look.
And those who were seen dancing were thought to be insane by those that could not hear the music -Nietzsche
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21-05-2014 12:36 PM
